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The SURPASS clinical trials included patients with stable cardiovascular disease, though those with unstable or severe cardiovascular conditions were typically excluded

Sixth, residual imbalance in HbA1c persisted after propensity score matching, indicating potential differences in baseline metabolic status between groups

As you eat smaller portions and consume different foods, the bacterial populations in your colon adapt, and some species produce more sulfur compounds as a metabolic byproduct

Clinically, GI problems usually appear in the first 2 to 6 weeks and often improve after 2 to 3 months if doses are increased gradually