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Additionally, disruptions in the blood-brain barrier in those with neurocognitive symptoms have been observed, as well as hypoperfusion in various organs, contributing to end-organ dysfunction [364, 365]

It's typically a short-lived phase as the body adjusts, but it can be unsettling if you're not expecting it

The microbiota is involved in numerous physiological processes, including digestion, immune modulation, and the production of essential vitamins and short-chain fatty acids (SCFAs) like butyrate, which contribute to intestinal barrier integrity and anti-inflammatory effects (Ahmed et al., 2022)

Blood 81 , 22232236 (1993)