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For instance, identification of suicidal outcomes by means of ICD codes registered during routine clinical practice databases has been associated with a slight under-registration of cases, which may result in underestimation of the association between drug exposure and SIS outcomes [35], and studies validating suicidal classification have concluded that ICD codes have good positive predictive value but low specificity [36]

Weight regain on discontinuation SURMOUNT-4 demonstrated approximately 14 percentage points of lost weight regained at 52 weeks post-tirzepatide discontinuation

Effects of lixisenatide versus liraglutide (short- and long-acting glp-1 receptor agonists) on esophageal and gastric function in patients with type 2 diabetes