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In addition, induction of apoptosis mediated by a dysregulated immune system and upstream regulation of inflammatory mediators has been observed by research studies
Inflammation markers, such as leukocytes, are recruited from the damage sites and then participate in the increased uptake of oxygen for the release of ROS and thus its accumulation
Additionally, GPX4 is a selenoprotein, thus a cells sensitivity to ferroptosis is related to selenium availability
Other symptoms of B12 deficiency, such as numbness and tingling in the hands and feet, are also common in people with diabetes and spinal stenosis
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