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In early 2025, the FDA ended the semaglutide shortage designation, which means compounding pharmacies no longer have the legal basis to produce copies of the drug

Seek urgent medical assistance if you develop: severe and persistent abdominal pain repeated vomiting or inability to keep fluids down swelling of the face, lips, tongue or throat difficulty breathing severe dizziness, confusion or fainting sudden loss or rapid deterioration of vision symptoms of severe low blood sugar when using insulin or a sulphonylurea Suspected adverse reactions can also be reported through the MHRA Yellow Card scheme

Semaglutide is not a replacement for insulin

How to navigate pricing in 2026 Rybelsus costs: With and without insurance coverage Frequently asked questions about insurance coverage for semaglutide Why is semaglutide often not covered by insurance