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Both prescription medications are classified as controlled substances, so they both are stringently monitored and come with the risk of abuse and physical or psychological dependence

About the author Medical Director Aesthetic & Regenerative Medicine Leading Silk Clinics with years of experience in aesthetic medicine, Dr Ahmad Sadeqyar oversees clinical excellence across all departments and personally treats complex aesthetic cases

In this way, JNK-mediated signal transduction, which can lead to apoptosis, is down-regulated [11], [12]

An expert safety panel reviewed it and found it safe when formulations are made to be non-irritating