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The relationship between Rybelsus and vision changes is complex: direct ocular toxicity is not established, but semaglutide has been associated with increased diabetic retinopathy complications in patients with pre-existing disease experiencing rapid HbA1c reduction

Elevated levels of T helper 17 (Th17) cells in both synovial tissue and peripheral blood of SONFH patients further highlight the link between T cells and disease progression

Typical medication side effects generally improve within several weeks as tolerance develops, whereas colitis symptoms often worsen or persist without treatment

RELATED STORIES That said, the strict daily schedule of taking a pill on an empty stomach with restrictions on food timing may be challenging for some people to stick to