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Weight regain can begin as early as eight weeks after stopping treatment, with average increases of 1.50 kg at eight weeks and 2.50 kg at 20 weeks compared to those who remained on the medication

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In the United States, a recent analysis of reports of perinatal exposure to GLP1RAs found a rise from less than 50 cases per 100,000 pregnancies in 2012 to over 200 cases per 100,000 pregnancies in 2020 [15] and a separate study in the US state of Maine showed that perinatal exposure to GLP1RAs rose from 0.02% in 2017 to 0.29% in 2023 [16]

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