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Doses include 5 mg, 7.5 mg, 10 mg, 12.5 mg, and a maximum of 15 mg per week

Consequently, in phase 2 and 3 trials with oral semaglutide, the recommendation was to administer oral semaglutide in the fasting state with up to 120 mL water and wait at least 30 min post-dose before eating or taking any other oral medications

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The AUC of metformin (administered at 850 mg twice daily for 4 days [trial 2]) was increased by 32% [90% confidence interval (CI) 1.231.43] in individuals receiving oral semaglutide and metformin versus those receiving metformin alone