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CS contains nicotine and other constituents which produce a high amount of reactive oxygen species (ROS) and causes an imbalance in the level of antioxidants in the body, thereby giving rise to oxidative stress 3

Andrew Black of the WHO Framework Convention on Tobacco Control Secretariat noted that smoking is an addiction largely taken up in childhood and adolescence, "so it is crucial to reduce the number of young people taking up smoking in the first place

Additionally, in specific spectral bands, the spectral characteristic peaks of materials frequently overlap, making it difficult to effectively distinguish material features

In a linked opinion piece in the journal five authors say that doctors should tell patients who smoke that lighting up puts them at extra risk of developing diabetes as well as cancer, stroke and heart attack.