Manzo E, Lorenzini I, Barrameda D, OConner AG, Barrows JM, Starr A, Kovalik T, Rabichow BE, Lehmkuhl EM, Shreiner DD, Joardar A, Livens J-C, Bowser R, Sattler R, Zarnescu DC (2019) Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS
Free radicals are unstable molecules that can lead to oxidative stress, which has been linked to various chronic diseases, including heart disease and cancer
CD4 + T cells from RA patients demonstrate decreased expression of the glycolytic rate-limiting enzyme PFKFB3 compared with healthy donor PBMCs, resulting in diminished pyruvate and ATP production (149)
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