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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Bi J., Newtson A.M., Zhang Y., Devor E.J., Samuelson M.I., Thiel K.W., Leslie K.K

Several additional GLP-1 receptor agonists also display neuroprotective properties in preclinical AD models

Methods Ethical statement All animal experiments were performed following the protocols approved by the Ethics Committee of the Animal Experimental Center of State Key Laboratory of Biotherapy of Sichuan University (Checking number: 20210409028)

When Combination Therapy May Be Appropriate and Safety Considerations GLP-1 plus DPP-4 combination therapy remains a niche strategy, reserved primarily for patients who have reached maximum tolerated GLP-1 doses, achieved partial glycemic control, and have contraindications to insulin or SGLT2 inhibitors