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A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis

The appetite suppression these drugs create makes it difficult to eat enough protein to preserve muscle mass, and roughly 25% of weight lost on GLP-1 drugs comes from lean tissue on average, with some trials reporting up to 40%

Plaintiffs allege that GLP-1 receptor agonists like Ozempic and Wegovy caused delayed gastric emptying, which has been documented in many cases through diagnostic imaging and gastroenterologist evaluations

"This makes them more likely to collapse and make it harder for you to breathe." People who are overweight are also more likely to hyperventilate, or breathe fast, he adds, which can worsen sleep apnea