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doi: 10.3390/ijms19020562

On the other hand, Repatha (evolocumab, Amgen) used the Pushtronex system (Wests SmartDose) and Ultomiris (ravulizumab, Alexion) also used SmartDose to deliver 3.5 mL of solution

2014;82:P7.245

More concerning but less common side effects include gallbladder problems , potential thyroid issues (a black box warning exists for medullary thyroid carcinoma risk in animal studies), and hair loss related to rapid weight loss rather than the medication itself