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Weight gain and obesity are associated with breast cancer recurrence, breast cancer-related death, and increased risk of heart disease and related complications

Given the importance of both methylation and de novo thymidylate biosynthesis processes and their obligate need to utilize 5,10-methyleneTHF, a strong rationale exists to examine genetic variation in key enzymes involved in both pathways in the context of the UVR influence on folate metabolism

In cervical cancer cells, the modifications after translations of NF-B were also reported to regulate tumor cell metastasis and invasion

A relative shift toward increased fat and reduced carbohydrate oxidation was observed with liraglutide