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The dose escalation to maintenance levels means all three receptor pathways are being activated at therapeutic concentrations

Upon oxidation, bilirubin is converted into various forms of bilirubin oxidation metabolites (BOMs), comprising at least seven hydrophilic metabolites that are promptly excreted into urine because of their hydrophilic nature (132)

A 4% drop in absolute LBM accompanying a 12% drop in body weight gives roughly 20% of weight loss as 'lean tissue.' Batsis reports closer to 35% and as Langer makes clear later in this piece, the gap between those numbers is partly explained by what DXA actually counts as 'lean

If youre taking antidepressants, continue them as prescribed and discuss any changes with your psychiatrist or prescribing physician