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Between 1999 and 2020, average daily cigarette consumption appears to have decreased overall in all age groups, though least among smokers aged 25-34 (Figure 1.10)

A 2023 study of the California Tobacco Control Program found that the program prevented the consumption of nearly 16 billion packs of cigarettes from 1989 to 2019, and that spending one more dollar per capita reduced average consumption of cigarettes per adult current smoker by about two packs a year

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In this study that included 1000 lung cancer cases and 1000 controls (Chinese population), it was found that the CFH Y402H genotypes were significantly overrepresented among lung cancer patients compared to controls, with the 402His/His or 402His/Try genotypes associated with a higher risk of lung cancer (OR = 1.50, 95% CI = 1.122.00)