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FIGURE 4 Nuclear factor erythroid 2-related factor (NRF2) is an accepted master regulator participating in the cellular adaptive response to redox or energy stress, which accumulates in nuclear to induce a battery of defensive genes encoding detoxifying enzymes and antioxidant proteins (such as SOD2 and NFB) (Figure 4E) (Tonelli et al., 2018)

In theory, a set of four ketoses can be obtained by using DHAP as the donor and the same aldehyde as the receptor (Gustavo, 2000)

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