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In some cases, taking Carnitine can have modest effects on weight loss, but it is important to stress that these effects have mainly been observed in obese or overweight people, and that the effects of Carnitine on weight loss can vary depending on individual characteristics

J Am Acad Dermatol 69:S15S26

NICE guidance does not recommend routine supplementation with NAD+ precursors as part of weight management or metabolic health strategies, reflecting the limited and inconsistent clinical evidence currently available for these products