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We observed a significantly elevated NADPH/NADP ratio in 1% O LCLs, suggesting a shift in redox balance to counteract hypoxia-induced reactive oxygen species (ROS) (S3B Fig)

Impact of oxidative stress on ascorbate biosynthesis in Chlamydomonas via regulation of the VTC2 gene encoding a GDP-L-galactose phosphorylase

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Moreover, liraglutide prevented the degradation of ECM components by downregulating matrix-degrading enzymes, such as MMP-3, suggesting that the GLP-1R agonist modulated the process of reducing the ER stress-related inflammatory response and alleviated the ECM catabolic process