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Prior work from our lab has demonstrated that even in the absence of caustic smoking-related stimuli, TCCSUP cell-derived EVs can promote the malignant transformation of immortalized human urothelial SV-HUC cells in a cargo protein-dependent manner 40

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"Flavored tobacco is a leading gateway to smoking addiction for our youth, which is why we must come together as a community to protect our young people from what too often becomes a lifelong and life-threatening habit," Emanuel said