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Koehler JA, Baggio LL, Yusta B, Longuet C, Rowland KJ, Cao X, et al

The structure shows that important hydrophobic ligand-receptor interactions are conserved in agonist- and antagonist-bound forms of the extracellular domain, but certain residues in the ligand-binding site adopt a GLP-1-specific conformation

Both the ADA and the AACE agree that the HbA1c goals should be individualized, but despite all the treatment options available, good glycemic control is not always attainable

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