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Several lawsuits have followed, including a notable case that saw employees awarded $20million after one employee faced a double lung transplant following complications caused by inhaling diacetyl at his workplace

It may have greater relevance in endotoxemia, where hepatic iNOS is most induced, versus models of remote localized inflammation, where CYP450 is downregulated and iNOS is not induced ( CYP450 mRNA suppression during the inflammatory response phase

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