semaglutide cardiovascular outcomes news 2025 october protects the heart beyond weight loss, SELECT trial shows semaglutide cardiovascular outcomes news 2025

Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment

In the broader GLP-1 receptor agonist literature, there is growing interest in the relationship between these medicines and hormonal or sexual health

Semaglutide may help some individuals reduce their alcohol use on days where they have at least 1 drink while also reducing cravings for alcohol

In our study, liraglutide prevented the TGF-1 + IL-1-induced augmentation of mitochondrial respiration in fibroblasts, indicating that activating GLP-1R could maintain mitochondrial homeostasis under inflammatory stress