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Effectiveness of Tirzepatide Tirzepatide has been shown to lead to significant weight lossup to 15% of body weight in clinical studies

The cascade of intracellular reactions triggered as a result leads to a decrease in the production of hunger-stimulating neuropeptides (specifically, neuropeptide Y) and, as a result, a relatively higher level of neuropeptides stimulating satiety

Weight loss can include both fat mass and lean mass, which is why protein intake and resistance training are often discussed alongside GLP-1 use

Ingredients that often end in ol can cause gas and bloating and so you may want to avoid them, especially if youre already having those side effects, says Tucker