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La introduccin de cambios en la cadena peptdica para reducir la degradacin por DPP-4, junto a la acilacin que facilita su unin no-covalente con la albmina, result en formulaciones de accin prolongada, posibilitando su aplicacin a la prctica clnica3,5

Summary Keywords antioxidant, bronchiectasis, COPD, cystic fibrosis, mucolytic, N-acetylcysteine Citation Barne M, Shevade M, Bhattacharyya P, Christopher DJ, Nair S, Abhyankar N, Halder I, Vora A, Khanna A, Swarnakar R, Chhajed P, Santhalingam B, Nair A and Salvi S (2026) N-acetylcysteine: evidence based consensus document on the therapeutic advantages in respiratory diseases (NECTAR)

Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism