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Br J Anaesth 2008 Oct

Pertinent to epilepsy, mice lacking mitochondrial SOD ( Sod2/ ) and heterozygous animals ( Sod2+/ ) show higher seizure susceptibility and concomitant degeneration, introducing the notion that O 2 are key players in the long-term brain changes after a seizure episode [22,23]

A review of the relationship between the gut microbiota and amino acid metabolism

5.3.6 Dopamine Recent studies have demonstrated that certain gut microbes can synthesize dopamine or its precursors through specific metabolic pathways, thereby indirectly regulating host physiological functions, and dopamine can stabilize GPX4 and mitigate ferroptosis-related oxidative stress (171)