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This suggested that regulation is concentrated in glial-rich border zones that control access to the brain

Curr Eye Res 2021;46:47081 7

Xiong T, Zeng J, Chen L, Wang L, Gao J, Huang L, et al

NAION is the most common optic neuropathy in adults over 50, caused by hypoperfusion of short posterior ciliary arteries supplying the optic nerve, inducing swelling that creates compartment syndrome compressing neighboring axons, resulting in ganglion cell death