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With insulin, there is risk of weight gain, for hypoglycemia, and theres more treatment burden and need for glucose monitoring. GLP-1 drugs have also been shown to have cardiovascular benefits, she adds, though further clinical trials are needed to assess orforgliprons effects on heart health
Our in vitro study found that compared to the single treatment, combination treatment with metformin and liraglutide was more effective to prevent PA-induced endothelial dysfunction, as indicated by inhibiting ROS production, and increasing NO level and eNOS phosphorylation
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Congdon EE, Ji C, Tetlow AM (2023) Tau-targeting therapies for Alzheimer disease: current status and future directions
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