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Treatment goals for nausea management are directed to prevent serious complications of persistent vomiting that could lead to hypovolemia and vitamin deficiencies that could lead to more serious conditions including but not limited to renal failure, cardiac abnormalities and electrolyte imbalances that could be fatal

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Having the commercial considerations built into the research process from the beginning -- cost, supply chain, consistency -- made all the difference compared to purely academic research that might identify something impossible to commercialize