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Ginkgo biloba B treatment has an inhibitory effect on lipid accumulation and ferroptosis caused by oxidative stress in MAFLD, possibly through the activation of the Nrf2 pathway, exerting an antioxidant effect

An illustration of the positive loop: GABA activates BDNF, which enhances GABA actions in immature neurons

In UC, a similar shift toward primary BAs and away from secondary BAs further disrupts epithelial tight junctions, perpetuating the cycle of inflammation and barrier dysfunction (131)

In the FOURIER study, in a group of patients with stable coronary artery disease treated with evolocumab, a 26.9% (6.246.7%) reduction of Lp(a) concentration was achieved, and a 23% incident reduction (HR = 0.77