Start with baseline metrics like weight, body measurements, and lab results (e.g., HbA1c, fasting glucose)
The approval represented a significant milestone as Wegovy became the first FDA-approved treatment for chronic weight management in adults since 2014, strengthening the adoption of long-acting GLP-1 analogues in obesity care In August 2021, results from the STEP 1 clinical trial of once-weekly semaglutide 2.4 mg were published in the New England Journal of Medicine, showing substantial weight reduction in adults with overweight or obesity without diabetes
Tirzepatide may be particularly valuable for patients with significant insulin sensitivity issues, fatty liver disease, or higher starting BMI values
It is also used to manage vitamin B12 deficiencies resulting from specific surgeries, diseases of the stomach or gut, and any other genetic disorders affecting vitamin B12 metabolism