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doi: 10.1210/er.2008-0027 33 LugerAPragerRGaubeSGrafHKlauserRSchernthanerG

Earlier meta-analyses did report a small on-medication motor benefit, roughly one to three points, but that effect is heterogeneous and fragile: in at least one pooled analysis, it lost statistical significance once the lixisenatide trial was removed [8]

When discussing potential dual therapy with your provider, sharing your genetic profile can support a more data-informed conversation about whether monotherapy, sequential therapy, or combination approaches align with your metabolic predispositions and clinical goals

Exercise benefits extend beyond improvements in liver outcomes, and have been shown to provide cardiovascular benefits, which is important as cardiovascular disease is a leading cause of death in this population