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18 F-FDG is taken up by tissues and trapped, and its accumulation is reflective of the tissues glycolytic activity ( 18 F-FDG imaging is limited to localized high-risk tumors and metastatic disease, indicating increased glucose uptake in rapidly growing malignant tissues and not indolent localized disease [ as reviewed in ( de novo lipogenesis in localized prostate cancer tissues compared to patient-matched benign tissues ( Lactate is produced via the reduction of pyruvate and is classically viewed as the by-product of excess glycolysis

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Twenty-four genes were identified that were differentially expressed in resistant or susceptible genotypes, including a tau class GST ( GSTU ) gene cluster (Wei et al., 2016

They still get sore, stiff, and fatigued, even if they keep pushing