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In 2021, it resulted in a mean weight loss of roughly 15% and maintenance through decreased appetite

Clinical studies have shown that endothelial dysfunction, hyperlipidemia, oxidative stress, and platelet hyperactivity are important factors in the development of atherosclerotic vascular problems (2)

Esters of sterols have a higher activity and better fat solubility, which allows for lower effective dosages (23 grams/day as opposed to 510 grams/day for unesterified sterols)

Standard UK treatment is intramuscular hydroxocobalamin injections, with loading doses followed by lifelong maintenance therapy for malabsorption causes