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Works through different neural pathways than GLP-1, which is why combining cagrilintide with semaglutide (CagriSema) enhances weight loss beyond either alone

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During and after dosing, no abnormalities were noted in the laboratory or clinical evaluations, and the patients reported no potentially drug- related adverse effects

Across the SURPASS phase 3 programme versus placebo and active comparators, including semaglutide, tirzepatide has shown superior dose-dependent reductions in HbA1c levels up to 2.5% and body weight up to 13%, compared with all comparators [88-91]