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recommended daily allowance (RDA) is: 2.4 micrograms (mcg) per day Certain groups may require higher intake, including: Pregnant women: 2.6 mcg daily Breastfeeding women: 2.8 mcg daily Older adults Vegetarians and vegans Individuals with absorption issues 500 mcg to 5000 mcg , which is significantly higher than the RDA but still generally considered safe when medically supervised

Gastrointestinal Distress: Acute systemic loads exceeding 10 mg frequently trigger nausea, severe cramping, and gastrointestinal rejection

Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States