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JoHelen McClain, a 72-year-old real estate agent from suburban Oklahoma City, had a simple goal when she started taking Wegovy in November of 2023

According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), hypothyroidism affects approximately 5% of the US population (including both overt and subclinical cases), with higher prevalence among women and older adults

Older adults with genetic predispositions toward insulin resistance may benefit from tirzepatide's dual-receptor action, while younger patients with specific GLP1R profiles might respond exceptionally well to semaglutide alone

Blood flow and fat distribution vary slightly between body regions, which may influence how quickly the medication enters the bloodstream