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Median direct R&D cost: $150 million (median: the value that falls exactly in the middle when all values in a dataset are arranged from smallest to largest) Average direct R&D cost: $369 million After adjustments (for opportunity costs and drugs that did not reach the market): Median: $708 million, Average: $1.3 billion When only two extremely costly drugs are excluded, the average cost drops to $950 million (26% lower)

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Responsibilities of DOD Officials The defense undersecretary for personnel and readiness should oversee readiness reporting policy development, manage the DRRS data exchange, create and maintain force elements with the DRRS Group Management module and develop a DRRS-compatible system for the registration of selected allied and partner forces needed to support strategic readiness assessments

doi:10.1016/j.jep.2014.06.056 Dwivedi S, Agarwal MP