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Single-cell omics unveils molecular lineages and remodeling mechanisms of the small airways In small airway stenosis, fibroblast-driven ECM remodeling is the core of structural stenosis, while persistent inflammation dominated by neutrophils and macrophages provides the cellular and enzymatic basis for this process (such as MMPs and ROS), promoting the degradation and redeposition of ECM (67, 68)

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The Pipes Draw Is Too Hard A tight draw is often linked to packing the pipe too strongly or not following the proper technique