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For most patients, symptoms improve over time as the body adapts to the medication, though some individuals may experience persistent symptoms requiring ongoing management or dose adjustment

Conjugated linoleic acid supplementation has shown limited evidence for weight loss, but studies have demonstrated an increase in oxidative stress and insulin resistance with regular consumption of conjugated linoleic acid, which limits its utilization

Therefore, it is essential to implement strategies to subside the symptoms associated with these conditions

In further support of this notion, GLP-1R agonists can still reduce food intake when the aversive pathways of the AP are inhibited