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Mar 2002;39(3):307-11

In order to improve outcomes, biphasic scaffolds can be created with a softer upper layer containing chondrogenic factors (e.g., TGF-, chondroitin sulfate) and a stiffer lower layer, often loaded with calcium phosphate, hydroxyapatite, or bone morphogenetic protein (BMP), to provide structural support of the above cartilage layer and to promote osteogenic tissue formation and boney integration

8 Bioavailability of curcumin The primary limitation in utilizing curcumins therapeutic potential stems from its intrinsic physicochemical characteristics

The peptide consists of three amino acids glycine, histidine, and lysine chelated to a copper(II) ion