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As mentioned earlier, federal prohibition has made research into the effects of cannabis largely observational, which can only detect correlation and not causation

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Indeed, within the context of European Union (EU) legislation, cigarillos are defined as a small type of cigar of a maximum weight of 3 g each 1,2 , with the difference between cigarettes versus both cigars and cigarillos defined primarily based on their outer wrapping 3 , definitions that we will use in this study