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Researchers followed more than 2,200 adults who had lost an average of 15% of their body weight over 76 weeks using semaglutide

Footnotes Abstract is updated and quality of figures is improved.

9 Proof-of-concept treatments were tested on patient fibroblasts and Pfa1 cells, which were knocked out of endogenous GPX4 and transfected to overexpress human mScarlet-tagged GPX4 WT (red) or GPX4 R152H (blue)