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These medications leverage the GLP-1 pathway to support weight loss by reducing appetite and increasing fullness

Some common side effects may include: Nausea Constipation or diarrhea Headache or fatigue Abdominal discomfort Rare but serious side effects can occur, such as gallbladder issues, increased heart rate, low blood sugar, pancreatitis, or allergic reactions

However, white matter OL lineage cells are more intrinsically regulated vs those in the gray matter, as transplantations into the adult mouse cerebral cortex revealed that white matter-derived cells differentiated into mature OLs in both niches with equal efficiency, whereas gray matter-derived cells did not 75

The Science of GLP-1 and Chronic Pain An interesting area of emerging research suggests that weight loss itself may help with the conditions for which gabapentin is prescribed