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10.1016/j.cellsig.2023.110955 93

Phase I and Phase II detoxification are two stages of the bodys natural process for breaking down and eliminating potentially harmful substances, including drugs, toxins, and metabolic waste products

The occurrence of ferroptosis in mature erythrocytes has not been confirmed and it seems quite challenging, since ferroptosis studies suffer from the lack of well-established markers and evaluation of this cell death requires a complex approach with identification of typical cellular and subcellular morphological alterations, genetic hallmarks, biochemical changes, expression of certain ferroptosis-related proteins, etc

m6A modification precisely controls gene expression by influencing mRNA stability, translation efficiency, and cellular localization [9,10,11]