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Analogous residues in other glutaredoxins were also shown to increase 11,20,31,56 or to decrease 18,55,56,57 their activity

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In summary, post-translational regulation of GPX4 provides new therapeutic entry points for OA intervention, but the strength of evidence, reproducibility, and clinical relevance of this research still need significant enhancement

After that it slowly disappeared because it became more and more difficult to obtain radioactive B12 suitable for human use, and at the same time less and less acceptable to use radioactive B12 in a diagnostic test