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In this regard, as 15LO1 increased, GPX4 expression concomitantly increased to balance the high 15LO1 activity (Figure 2C)

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GHK-Cu also influences the ubiquitin-proteasome system (UPS), upregulating dozens of genes involved in protein degradation and cellular maintenance, thereby supporting proteostasis under stress conditions (Pickart and Margolina 2018)

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However, in areas with limited data, the cost of manual investigations is high and the policies may lack quantitative measurements

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