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KPV's small molecular weight (3 amino acids) and its derivation from a naturally occurring hormone fragment suggest a favorable safety profile, but human trial data is needed
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proposed that exenatide upregulates uncoupling protein-3 (UCP-3) and nuclear respiratory factor-1 (Nrf-1) in cardiomyocytes subjected to ischemia/reperfusion (I/R) via the cAMP/PKA pathway, thereby facilitating mitochondrial homeostasis [93]
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