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The corresponding pharmacokinetic parameters are listed as follows: T max = 0.167 h, C max = 155 11.8 ng Eq./ml, AUC 0t = 4945 417 h ng Eq./ml, AUC 0 = 12956 2074 hng Eq./ml, average residence time (MRT 0-t ) of plasma total radioactivity = 33.2 1.03 h, and t 1/2 = 102 h (Table 9)
Glaucoma damages optic nerve through elevated intraocular pressure or vascular insufficiency causing progressive vision loss
Those who try to stretch every last day out of a vial end up with data they cannot trust
Only the portion of drugs that overcome the barriers like the blood-brain barrier and then reach their targets, such as the central nervous system or cancer cells can be considered bioavailable
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